HomeAll ports of departurePanama City

Cruise from Panama City

Panama City, the capital of Panama, is a vibrant and cosmopolitan metropolis, where a rich history meets a dynamic modern culture. The city is a mix of old and new, the historic districts live in perfect harmony with modern infrastructure. On the one hand, visitors have the opportunity to visit many historical attractions. The best way to learn about the history and operations of the canal is to visit the Miraflores locks or, if you want to deepen your knowledge related to the history of the city, visiting the Casco Viejo or Panama Viejo neighborhoods is the best choice.

In Casco Viejo, a UNESCO World Heritage Site,you can admire examples of colonial architecture, a lively nightlife and cultural landmarks such as the Panama Cathedral and the Presidential Palace, while Panama Viejo offers the opportunity to visit the ruins of the original city and provides a glimpse into the early history of Panama.

11 cruises
Panama City Itinerary Central America
Suite from $7,701
price per person Taxes included
Explora III | Apr 22, 2027
Duration: 11 nights
Departure from: Panama City Landing: Los Angeles
Itinerary:
1. Panama City,
2. navigation,
3. navigation,
4. Acajutla,
5. Puerto Quetzal,
6. Ciudad Madero,
7. Huatulco,
8. navigation,
9. Puerto Vallarta,
10. navigation,
11. navigation,
12. Los Angeles
Panama City Itinerary
Suite Balcony from $8,085
price per person Taxes included
Scenic Eclipse | Oct 26, 2026
Duration: 9 nights
Departure from: Panama City Landing: Valparaiso
Itinerary:
1. Panama City,
2. navigation,
3. navigation,
4. navigation,
5. navigation,
6. navigation,
7. navigation,
8. navigation,
9. navigation,
10. Valparaiso
Panama City Itinerary Central America
External from $8,144
price per person Taxes included
Emerald Azzurra | Jan 24, 2028
Duration: 7 nights
Departure from: Panama City Landing: Puntarenas
Itinerary:
1. Panama City,
2. Isla San José,
3. Darien Jungle,
4. Cebaco Island,
5. Golfito,
6. Quepos,
7. Tortuga,
8. Puntarenas
Panama City Itinerary Central America
External from $10,683
price per person Taxes included
Emerald Azzurra | Jan 24, 2029
Duration: 7 nights
Departure from: Panama City Landing: Puntarenas
Itinerary:
1. Panama City,
2. Isla San José,
3. Darien Jungle,
4. Cebaco Island,
5. Golfito,
6. Quepos,
7. Tortuga,
8. Puntarenas
Panama City Itinerary South America
Suite from $11,864
price per person Taxes included
Scenic Eclipse | Oct 31, 2027
Duration: 13 nights
Departure from: Panama City Landing: Valparaiso
Itinerary:
1. Panama City,
2. navigation,
3. navigation,
4. navigation,
5. Manta,
6. navigation,
7. Salaverry,
8. navigation,
9. navigation,
10. navigation,
11. navigation,
12. navigation,
13. navigation,
14. Valparaiso
11 cruises

Departure calendar

Browse the catalog of all cruises departing from Panama City now and find the one that suits your needs best.

  • 2027
  • 2028
  • 2029
October 2026 November 2026 December 2026
January 2027 February 2027 March 2027 April 2027 May 2027 June 2027 July 2027 August 2027 September 2027 October 2027 November 2027 December 2027
January 2028 February 2028 March 2028 April 2028 May 2028 June 2028 July 2028 August 2028 September 2028 October 2028 November 2028 December 2028
January 2029 February 2029 March 2029
On the other hand, Panama City is currently known for its impressive skyline that reflects its status as a financial center. The modern culture of the city is especially visible in the banking area and along one of the city's main streets, Calle 50, where large shiny glass buildings follow one another.

All ships departing from Panama City

From the smallest and most intimate to the largest and most technological: find out which ships are departing from {port}.