Search among available cruises
Filter Cruises
home ›

Cruises of Royal Caribbean in Panama

  • 2025
  • 2026
  • 2027
October 2025 November 2025 December 2025
January 2026 February 2026 March 2026 April 2026 May 2026 June 2026 July 2026 August 2026 September 2026 October 2026 November 2026 December 2026
January 2027 February 2027 March 2027 April 2027
78 cruises

Caribbean: Panama, Colombia, Netherlands Antilles, Aruba

Colon Itinerary Caribbean
from $1,666
price per person Taxes included
7 reservations in 36 hours
Flash Sale Refundable Deposit Promo
See the cruise Book
Serenade Of The Seas | 11 Oct 2025
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Willemstad,
5. Oranjestad,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from $1,537
price per person Taxes included
7 reservations in 36 hours
Flash Sale Refundable Deposit Promo
See the cruise Book
Serenade Of The Seas | 18 Oct 2025
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Oranjestad,
5. Willemstad,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Netherlands Antilles, Aruba

Colon Itinerary Caribbean
from $1,666
price per person Taxes included
4 reservations in 36 hours
Flash Sale Refundable Deposit Promo
See the cruise Book
Serenade Of The Seas | 25 Oct 2025
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Willemstad,
5. Oranjestad,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from $1,655
price per person Taxes included
7 reservations in 48 hours
Flash Sale Refundable Deposit Promo
See the cruise Book
Serenade Of The Seas | 1 Nov 2025
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Oranjestad,
5. Willemstad,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Netherlands Antilles

Colon Itinerary Caribbean
from $1,535
price per person Taxes included
8 reservations in 48 hours
Flash Sale Refundable Deposit Promo
See the cruise Book
Serenade Of The Seas | 8 Nov 2025
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Kralendijk,
5. Willemstad,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from $1,431
price per person Taxes included
Flash Sale Refundable Deposit Promo
See the cruise Book
Serenade Of The Seas | 15 Nov 2025
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Oranjestad,
5. Willemstad,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from $1,423
price per person Taxes included
8 reservations in 36 hours
Flash Sale Refundable Deposit Promo
See the cruise Book
Serenade Of The Seas | 22 Nov 2025
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. navigation,
5. Oranjestad,
6. Willemstad,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Netherlands Antilles

Colon Itinerary Caribbean
from $1,418
price per person Taxes included
8 reservations in 48 hours
Flash Sale Refundable Deposit Promo
See the cruise Book
Serenade Of The Seas | 29 Nov 2025
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Kralendijk,
5. Willemstad,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from $1,407
price per person Taxes included
Flash Sale Refundable Deposit Promo
See the cruise Book
Serenade Of The Seas | 6 Dec 2025
Duration: 6 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Oranjestad,
5. Willemstad,
6. navigation,
7. Colon

Caribbean: Panama, Colombia, Netherlands Antilles, Aruba

Colon Itinerary Caribbean
from $1,810
price per person Taxes included
8 reservations in 48 hours
Flash Sale Refundable Deposit Promo
See the cruise Book
Serenade Of The Seas | 12 Dec 2025
Duration: 8 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. navigation,
3. Cartagena De Indias,
4. navigation,
5. Kralendijk,
6. Oranjestad,
7. Willemstad,
8. navigation,
9. Colon

Caribbean: Panama, Colombia, Netherlands Antilles, Aruba

Colon Itinerary Caribbean
from $1,571
price per person Taxes included
5 reservations in 36 hours
Flash Sale Refundable Deposit Promo
See the cruise Book
Serenade Of The Seas | 20 Dec 2025
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. navigation,
5. Willemstad,
6. Oranjestad,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from $2,002
price per person Taxes included
6 reservations in 36 hours
Flash Sale Refundable Deposit Promo
See the cruise Book
Serenade Of The Seas | 27 Dec 2025
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Oranjestad,
5. Kralendijk,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Netherlands Antilles, Aruba

Colon Itinerary Caribbean
from $1,299
price per person Taxes included
4 reservations in 36 hours
Flash Sale Refundable Deposit Promo
See the cruise Book
Serenade Of The Seas | 3 Jan 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. navigation,
5. Kralendijk,
6. Oranjestad,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from $1,481
price per person Taxes included
Flash Sale Refundable Deposit Promo
See the cruise Book
Serenade Of The Seas | 10 Jan 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Oranjestad,
5. navigation,
6. Willemstad,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Netherlands Antilles, Aruba

Colon Itinerary Caribbean
from $1,501
price per person Taxes included
5 reservations in 36 hours
Flash Sale Refundable Deposit Promo
See the cruise Book
Serenade Of The Seas | 17 Jan 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Kralendijk,
5. Oranjestad,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from $1,382
price per person Taxes included
Flash Sale Refundable Deposit Promo
See the cruise Book
Serenade Of The Seas | 24 Jan 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Oranjestad,
5. Kralendijk,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from $1,380
price per person Taxes included
7 reservations in 48 hours
Flash Sale Refundable Deposit Promo
See the cruise Book
Serenade Of The Seas | 31 Jan 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Oranjestad,
5. Kralendijk,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from $1,251
price per person Taxes included
4 reservations in 36 hours
Flash Sale Refundable Deposit Promo
See the cruise Book
Serenade Of The Seas | 7 Feb 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Oranjestad,
5. Kralendijk,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from $1,380
price per person Taxes included
6 reservations in 36 hours
Flash Sale Refundable Deposit Promo
See the cruise Book
Serenade Of The Seas | 14 Feb 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. navigation,
5. Oranjestad,
6. Willemstad,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Netherlands Antilles, Aruba

Colon Itinerary Caribbean
from $1,197
price per person Taxes included
6 reservations in 48 hours
Flash Sale Refundable Deposit Promo
See the cruise Book
Serenade Of The Seas | 21 Feb 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. navigation,
5. Kralendijk,
6. Oranjestad,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Netherlands Antilles, Aruba

Colon Itinerary Caribbean
from $1,249
price per person Taxes included
Flash Sale Refundable Deposit Promo
See the cruise Book
Serenade Of The Seas | 28 Feb 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. navigation,
5. Kralendijk,
6. Oranjestad,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from $1,253
price per person Taxes included
4 reservations in 48 hours
Flash Sale Refundable Deposit Promo
See the cruise Book
Serenade Of The Seas | 7 Mar 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Oranjestad,
5. navigation,
6. Willemstad,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Netherlands Antilles, Aruba

Colon Itinerary Caribbean
from $1,249
price per person Taxes included
Flash Sale Refundable Deposit Promo
See the cruise Book
Serenade Of The Seas | 14 Mar 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Willemstad,
5. Oranjestad,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from $1,249
price per person Taxes included
4 reservations in 36 hours
Flash Sale Refundable Deposit Promo
See the cruise Book
Serenade Of The Seas | 21 Mar 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. navigation,
5. Oranjestad,
6. Willemstad,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from $1,592
price per person Taxes included
5 reservations in 48 hours
Flash Sale Refundable Deposit Promo
See the cruise Book
Serenade Of The Seas | 28 Mar 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. navigation,
5. Oranjestad,
6. Kralendijk,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from $1,299
price per person Taxes included
5 reservations in 48 hours
Flash Sale Refundable Deposit Promo
See the cruise Book
Serenade Of The Seas | 4 Apr 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. navigation,
5. Oranjestad,
6. Willemstad,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Netherlands Antilles, Aruba

Colon Itinerary Caribbean
from $1,303
price per person Taxes included
4 reservations in 48 hours
Flash Sale Refundable Deposit Promo
See the cruise Book
Serenade Of The Seas | 11 Apr 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Willemstad,
5. Oranjestad,
6. navigation,
7. navigation,
8. Colon
sold out

Panama, Colombia, Netherlands Antilles, Aruba

Colon Itinerary Caribbean
from $1,555
price per person Taxes included
Serenade Of The Seas | 18 Apr 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Willemstad,
5. Oranjestad,
6. navigation,
7. navigation,
8. Colon

Central America: Panama, Costa Rica, Mexico, United States

Colon Itinerary Central America
from $1,709
price per person Taxes included
3 reservations in 48 hours
Flash Sale Refundable Deposit Promo
See the cruise Book
Serenade Of The Seas | 25 Apr 2026
Duration: 10 nights
Departure from: Colon Landing: Los Angeles
Itinerary:
1. Colon,
2. navigation,
3. navigation,
4. Puntarenas,
5. navigation,
6. Huatulco,
7. navigation,
8. Puerto Vallarta,
9. navigation,
10. navigation,
11. Los Angeles

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from $1,109
price per person Taxes included
Flash Sale Refundable Deposit Promo
See the cruise Book
Jewel Of The Seas | 9 May 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Oranjestad,
5. Willemstad,
6. navigation,
7. navigation,
8. Colon
78 cruises