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Departure calendar San Antonio

Browse the catalog of all cruises departing from San Antonio now and find the one that suits your needs best.

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Cruises from San Antonio

San Antonio, located along the coast of the Pacific Ocean, is a vibrant and economically significant city that perfectly combines its strategic port operations with rich cultural and historical elements. The Port of San Antonio is the busiest port in Chile and one of the largest in South America. It plays a crucial role in the country's economy, handling a significant portion of Chile’s imports and exports and making San Antonio one of Chile’s most important port cities.

The city is reknown for its beautiful beaches, historic sites and cultural events. Firstly, San Antonio boasts several beaches that attract both locals and tourists, such as Llolleo Beach and Cartagena Beach, which are popular for their scenic views and recreational activities.

12 cruises

South America: Chile, Argentina, Falkland Islands, Uruguay

San Antonio Itinerary South America
from $2,172
price per person Taxes included
See the cruise Book
Oosterdam | Dec 4, 2025
Duration: 14 nights
Departure from: San Antonio Landing: Buenos Aires
Itinerary:
1. San Antonio,
2. navigation,
3. Puerto Montt,
4. Puerto Chacabuco,
5. navigation,
6. navigation,
7. navigation,
8. Punta Arenas,
9. navigation,
10. Ushuaia,
11. navigation,
12. Port Stanley,
13. navigation,
14. navigation,
15. Montevideo,
16. Buenos Aires,
17. Buenos Aires

South America: Chile, Argentina, Falkland Islands, Uruguay

San Antonio Itinerary South America
from $2,796
price per person Taxes included
See the cruise Book
Sapphire Princess | Dec 6, 2025
Duration: 16 nights
Departure from: San Antonio Landing: Buenos Aires
Itinerary:
1. San Antonio,
2. navigation,
3. Puerto Montt,
4. Puerto Chacabuco,
5. navigation,
6. navigation,
7. Punta Arenas,
8. Ushuaia,
9. Cape Horn,
10. Port Stanley,
11. navigation,
12. Puerto Madryn,
13. navigation,
14. navigation,
15. Montevideo,
16. Buenos Aires,
17. Buenos Aires

South America: Chile, Argentina, Falkland Islands, Uruguay

San Antonio Itinerary South America
from $6,504
price per person Taxes included
1 booking in 72 hours
See the cruise Book
Oosterdam | Jan 9, 2026
Duration: 22 nights
Departure from: San Antonio Landing: Buenos Aires
Itinerary:
1. San Antonio,
2. navigation,
3. Puerto Montt,
4. Puerto Chacabuco,
5. navigation,
6. navigation,
7. navigation,
8. Punta Arenas,
9. navigation,
10. Ushuaia,
11. Cape Horn,
12. navigation,
13. navigation,
14. navigation,
15. navigation,
16. navigation,
17. navigation,
18. Port Stanley,
19. navigation,
20. Puerto Madryn,
21. navigation,
22. Punta Del Este,
23. Montevideo,
24. Buenos Aires,
25. Buenos Aires

South America: Chile, Argentina, Falkland Islands, Uruguay

San Antonio Itinerary South America
from $3,509
price per person Taxes included
See the cruise Book
Oosterdam | Feb 22, 2026
Duration: 14 nights
Departure from: San Antonio Landing: Buenos Aires
Itinerary:
1. San Antonio,
2. navigation,
3. Puerto Montt,
4. Puerto Chacabuco,
5. navigation,
6. navigation,
7. navigation,
8. Punta Arenas,
9. navigation,
10. Ushuaia,
11. navigation,
12. Port Stanley,
13. navigation,
14. navigation,
15. Montevideo,
16. Buenos Aires,
17. Buenos Aires

South America: Chile, Peru, Panama

San Antonio Itinerary South America
from $4,925
price per person Taxes included
3 reservations in 72 hours
See the cruise Book
Azamara Quest | Mar 2, 2026
Duration: 13 nights
Departure from: San Antonio Landing: Balboa
Itinerary:
1. San Antonio,
2. Coquimbo,
3. navigation,
4. Iquique,
5. Arica,
6. navigation,
7. Pisco,
8. Lima,
9. Lima,
10. navigation,
11. navigation,
12. navigation,
13. Balboa,
14. Balboa
12 cruises

Secondly, the city has several historical sites and landmarks, including the San Antonio Lighthouse and the picturesque Paseo Bellamar, a waterfront promenade. Finally, San Antonio hosts cultural events and festivals that showcase local traditions, music and cuisine.

All ships departing from San Antonio

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Oosterdam Images of Oosterdam Sapphire Princess Images of Sapphire Princess Azamara Journey Images of Azamara Journey Azamara Quest Images of Azamara Quest Seabourn Pursuit Images of Seabourn Pursuit